Endocrine Abstracts

Introduction: Parathyroid carcinoma is a rare cause of hyperparathyroidism. In most cases, hyperparathyroidism is caused by a single benign adenoma. The vast majority of the remaining cases are caused by parathyroid hyperplasia or multiple adenomas. We present here a case of a young Filipina who presented with multiple fractures on all extremities and bilateral parathyroid adenoma.Case presentation: A 19-year-old Filipina presented with bone pains for 7 ...

Background: Pregnancy has a profound impact on the thyroid gland and its function. Severe thyrotoxicosis can lead to many complications and endanger the mother or fetus. Antithyroid drug (ATD), at its lowest possible dose, should be given. However, one of the complications of treatment include agranulocytosis which is a rare but serious allergic event with a prevalence of 0.1 to 0.5 percent. Thus, alternative treatment should be prescribed because a cross-reaction between ATDs...

Background: Idiopathic hypogonadotropic hypogonadism (IHH) is manifested as absent or incomplete puberty and biochemically low levels of sex hormones, with low or inappropriately normal gonadotropin hormones. In the absence of structural or functional lesions of the hypothalamic or pituitary gland, the hypogonadism is referred as idiopathic hypogonadotropic hypogonadism (IHH). IHH is a genetically heterogeneous disorder which can be caused by pathogenic variants affecting prot...

Background: Non-ketotic hyperglycemia hemichorea is a movement disorder characterized by irregular, involuntary and abrupt hyperkinetic movements caused by hyperglycemia. The pathophysiology remains unclear however there are several theories on its mechanism. The diagnosis is confirmed by presence of involuntary irregular movements combined with findings of hyperdensities on the basal ganglia in cranial computed tomography scan (CT-scan) or magnetic resonance imaging scan (MRI...

Introduction: The effect of self-prescribed cross-sex hormone therapy on Male-to-Female (MtF) transgenders do not appear to have been well investigated and can be associated with potential serious longterm complications. The main purpose of this study is to look at the clinical and metabolic profile, and cardiovascular outcomes of MtF transgenders in Zamboanga Peninsula.Methodology: This is a cross-sectional study, done to determine the clinical and meta...

Introduction: The effect of self-prescribed cross-sex hormone therapy on Male-to-Female (MtF) transgenders do not appear to have been well investigated and can be associated with potential serious longterm complications. The main purpose of this study is to look at the clinical and metabolic profile, and cardiovascular outcomes of MtF transgenders in Zamboanga Peninsula.Methodology: This is a cross-sectional study, done to determine the clinical and meta...

A 49 year-old Filipino male presented at the emergency room because of progressive dyspnea. He was diagnosed with papillary thyroid carcinoma by fine needle aspiration biopsy of his 7×5 cm thyroid mass 3 months prior to his current consultation. He was scheduled to undergo total thyroidectomy but he opted to postpone his surgery due to intermittent cough. On admission, a pulmonary mass with pleural effusion on the right was noted on chest radiograph. He was considered to ...

Insulin resistance (IR) has been proven to increase the risks for cardiovascular complications in type 2 diabetes mellitus. Recently, IR has also been shown to play a bigger role in the natural history of type 1 diabetes mellitus (T1DM) disease process than is commonly recognized. The objectives of this study are to determine the prevalence of IR among Filipino adults with T1DM and to describe the clinical features of T1DM with IR.This cross-sectional an...

We report two rare cases of well differentiated thyroid-type carcinoma arising from struma ovarii managed in our institution.Case 1: A 41-year-old female admitted due to abdominal pain and vomiting. Her abdomen was globular with palpable vague mass on lower abdomen. Ultrasound scan revealed 12.5×12.1×8.3 cm heterogenous mass with ascites. Total abdominal hysterectomy with bilateral salphingo-oophorectomy was done and histopathology results reve...

A. Background/Significance: Autoimmune polyglandular syndrome Type II (APS-II) is a rare polyendocrinopathy with a prevalence of 1 to 2 in 100.000, instigated by immune-mediated destruction of several organs. Knowledge of APS-II is crucial, especially in the early detection of polyglandular disorder among patients with endocrine autoimmunity. B. Case: This case is of a 40-year-old male who initially presented with Grave′s disease after showing sign...